Live Cell Super-Resolution Imaging Research Team

We elucidate molecular mechanisms of protein sorting and transport in membrane traffic
January 20, 2024
An article on the Golgi project by Nakano Team has been published in Impact Journal.
August 23, 2023
The collaborative paper with Obata et al.(Cell Rep.)"Golgi retention and oncogenic KIT signaling via PLCg2-PKD2-PI4KIIIb activation in gastrointestinal stromal tumor cells" has been published.
July 21, 2023
The collaborative paper with Toshima et al.(eLife)"The yeast endocytic early/sorting compartment exists as an independent sub-compartment within the trans-Golgi network" has been published.
April 1, 2023
Due to the age rule, Nakano steps down from the Team Leader position and Center Director Midorikawa serves as TL concurrently. Nakano stays in the team as a Deputy Team Leader.
April 7, 2021
The paper by Shimizu et al. (Nat. Commun.) was selected as an Editors' Highlight.
August 2, 2019
The paper by Tojima et al. (J. Cell Sci.) was selected for First Person Interview.
July 9, 2019
The paper by Kurokawa et al. (J. Cell Biol.) was selected as an outstanding article by JCB and appeared in July Highlights from JCB: Lipid and Membrane Biology Collection.
May 17, 2019
The paper by Kurokawa et al. (J. Cell Biol.) was described as Research Highlight in RIKEN Research.
Feb 1, 2019
Webpage of the NAKANO Laboratory was renewed.



We are studying membrane trafficking, the molecular mechanisms of protein transport and sorting and the roles of membrane traffic in higher-order functions of multicellular organisms, plants in particular.


Subject1 Subject1

Membrane Traffic in Yeast Cells

Subject2 Subject2

Membrane Traffic in Plant Cells

Subject3 Subject3

Membrane Traffic in Animal Cells

Subject4 Subject4

Development of High-speed and High-resolution Live Imaging Microscopy That Is Needed for Membrane Traffic Research


JSPS Grant-in-Aid for Scientific Research (S) FY2018-FY2022
Full elucidation of sorting mechanisms in and around the Golgi apparatus by super-resolution live imaging
PI: Akihiko Nakano (RIKEN Center for Advanced Photonics)
MEXT Grant-in-Aid for Scientific Research on Innovative Areas FY2017-FY2021
Toward an integrative understanding of functional zones in organelles
Leader: Shigeomi Shimizu (Tokyo Medical and Dental University)
Study of the sorting zone for GPI-anchored proteins at ER exit sites
PI: Akihiko Nakano (RIKEN Center for Advanced Photonics)

Latest Publications

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